Ugi reaction Thesis Example | Topics and Well Written Essays - 1500 words

Ugi reaction - Thesis Example Ugi Reaction The Ugi reaction subject has gained unprecedented prominent in recent chemical literature. An explosion of interest toward the Ugi reaction is explained by the rapid development of chemical technologies and the need to solve organic chemistry challenges in a cost-efficient manner. The history of the Ugi reaction dates back to the middle of the 20th century, but it was not before the beginning of the 21st century that its value and benefits for the evolution of organic chemistry were consistently recognized. Ivar Ugi is believed to be the father of all multicomponent reactions [28]. Ugi is also considered the grandfather of the whole combinatorial chemistry [29]. Today’s chemists rely on the advantages of the Ugi reaction, to synthesize diverse collections/ libraries of biologically interesting products. This is particularly the case of the drug industry, which relies on the premise of discovery and innovations and demands fast methods of chemical analysis and synt hesis of complex molecules. The Ugi reaction is a popular object of contemporary chemical research. Dozens of studies were performed to understand the hidden benefits of the Ugi reaction and its implications for chemistry. â€Å"The Ugi reaction is the one-pot condensation of an amine, aldehyde or ketone, isocyanide, and a nucleophile to afford ?-substitute carboxamide derivatives† [17]. ... The carboxylic acid is then added together with the imino carbon; acyl transfer rearranges the resulting acylated isoamide, leading to the creation of the desired product [17]. The benefits of the Ugi reaction are numerous. The Ugi reaction is believed to be the most convenient instrument for generating diverse libraries of chemical compounds [8; 9]. That the reaction occurs at room temperature also means that the reaction is relatively simply and cost-effective: it does not require using artificial additions and can be easily held without complex temperature-regulating mechanisms [9]. The Ugi reaction is extremely advantageous for generating pharmacologically active compounds and diverse molecules [9]. For example, it was extensively used to synthesize anti-malarial agents [9]. Most, if not all, Ugi reaction products tend to precipitate in pure form [9; 15; 21]. This is extremely important for the success of other chemical processes, as long as compound mixtures obtained during the Ugi reaction do not require costly purification prior to being used in other chemical procedures [6; 27]. For example, the Ugi reaction does not require the use of costly chromatography and, consequentially, reduces the costs of the process and the final product. Eventually, almost all compounds obtained during the Ugi reaction are quantifiable [6; 38]. No information about potential drawbacks of the Ugi reaction has been available so far. The current state of literature provides extensive information about the Ugi reaction and its practical applications. This is mostly because the Ugi reaction is gradually turning into the key element of chemical research and analysis, especially in the pharmaceutical industry. More and more chemical compounds are

Differences Between Qualitative And Quantitative Research English Language Essay

Differences Between Qualitative And Quantitative Research English Language Essay The aim of the dissertation is to examine the strategies construction professionals are adopting to survive the economic slowdown, particularly by seeking work overseas. At present construction professionals are forced to flee Ireland in order to survive this recession. This dissertation will examine the difficulties and challenges facing these construction professionals moving abroad and how they adapt to working in these foreign countries. The following report was undertaken in order to understand the processes involved with data collection and how to go about it in order to carry out the dissertation. The different types of data collection are explored and their advantages and disadvantages taken into account. This is attained through the critical analysis of qualitative and quantitative research, the different methods of data collection and the feasibility of each method. The positive and negative aspects of these research studies are explored to ascertain the benefits each would have in relation to the dissertation. For the benefit of this project and the chosen dissertation topic, I have chosen to research questionnaires, interviews and case studies. Quantitative Research Quantitative research sources hard and reliable facts on a topic area. Quantitative research is an injury into a social or human problem, based on testing a hypothesis or a theory composed of variables, measured with numbers, and analysed with statistical procedures, in order to determine whether the hypothesis or the theory hold true . (Naoum, 1998 p38) Qualitative Research Qualitative research sources opinions and perceptions on a topic area. Qualitative research†¦..it emphasiss meanings, experiences (often verbally described), description and so on. (Naoum, 1998, p40) Quantitative versus Qualitative Research Quantitative research is used when finding out the facts of a concept, for example a question or an attribute. This research method is also used when collecting factual evidence. A study can then be made on the relationship of these facts in order to test a particular theory or hypothesis. Qualitative research is subjective in nature. In other words it has an emphasis on meanings, experiences and descriptions. Information collected in qualitative research can be either i) exploratory or ii) attitudinal. i) Exploratory Research This is used when the researcher has a limited knowledge of the topic. An example of exploratory research is the interview technique. The purpose of this type of research is the need for a clear and precise statement of the recognised problem. Exploratory research may be conducted for three interrelated reasons; diagnosing a situation, screening alternatives or to discover new ideas. Data provided is the words of those interviewed and what they have exactly said or a description of what has been observed. Examples of questions used in an exploratory search may be; Questions with the words What or How. Non-directional worded questions. Open ended questions. Questions that may evolve during the study. ii) Attitudinal Research Attitudinal research is used to subjectively evaluate the opinion, view or perception of a person towards a particular object. Opinion and views can be evaluated for the benefit of this study by using subjective questions like; Do you think moving abroad to seek employment is the key to survival? Please indicate which of the following is most important to ensure maximum motivation in workers†¦. Questions ending in please express your level of agreement. There is no correct or incorrect answer to these questions as they all require an individual opinion. In a quantitative study, the hypothesis is best understood when applied in a theoretical framework. A theory is used deductively and is placed at the beginning of a study. The objective is to then collect data and test it. The result of this data will then reflect on whether the theory was confirmed or unconfirmed. In qualitative research the use of theory is less clear because there is no standard rule of placement. The placement of theory will not be placed at the beginning of the study but closer to the end. A theory may emerge during the data collection or be used late in the research process as a basis for comparison with another theory. Quantitative and qualitative research can be compared using the analogy that quantitative research is taking into account the shape or design of an object where as qualitative research is living and feeling this object. Qualitative Advantages Provides depth and detail, looking deeper than analysing ranks and counts by recording attitudes, feelings and behaviours. Creates openness as it  encourages people to expand on their responses and can open up new topic areas not initially considered. Disadvantages Usually fewer people are studied as the collection of qualitative data is generally more time consuming than quantitative data collection. Because fewer people are generally studied it is not possible to generalise results to that of the population. Usually exact numbers are reported rather than percentages. It is difficult to make systematic comparisons for example, if people give widely differing responses that are highly subjective. Quantitative Advantages Allows for a broader study, involving a greater number of subjects, and enhancing the generalisation of the results. Can allow for greater objectivity and accuracy of results. Using standards means that the research can be replicated, and then analysed and compared with similar studies. Personal bias can be avoided by researchers keeping a distance from participating subjects and employing subjects unknown to them Disadvantages Collect a much narrower and sometimes superficial dataset Results are limited as they provide numerical descriptions rather than detailed narrative and generally provide less elaborate accounts of human perception The research is often carried out in an unnatural, artificial environment so that a level of control can be applied to the exercise. This level of control might not normally be in place in the real world yielding laboratory results as opposed to real world results In addition preset answers will not necessarily reflect how people really feel about a subject and in some cases might just be the closest match. The development of standard questions by researchers can lead to structural bias and false representation, where the data actually reflects the view of them instead of the participating subject. Both qualitative and quantitative research will be relevant to the authors dissertation. This will be displayed through the use of both factual evidence obtained from publications and further literature and also through interviewing those who have fled Ireland to seek work overseas. Analysis of Different Methods of Data Collection The approach one should adopt when conducting data collection should depend on the nature of the case study and the type of data and information that is required and available at that time. There are many approaches available to study however many require long periods of time and emphasise detailed evidence. There are two main sources of information: i) Primary Data ii) Secondary Data Primary Primary literature is the most accurate source of information as it publishes original research. (Naoum, 1998, p19) The primary data can be collected from past case studies, questionnaires, formal interviews and reports. Secondary Secondary literature sources are these that cite from primary sources such as textbooks, and newspaper articles. (Naoum, 1998, p22) The secondary data can be collected from textbooks, construction magazines and newspaper articles. Fieldwork Research Fieldwork research refers to the methods of primary data collection used by the researcher. Three practical approaches to Fieldwork are; i) The survey approach. ii) The case study approach. iii) The problem solving approach. For the benefit of the Authors dissertation we will now explore The Case Study, Interview and Questionnaire Approach as this holds the most relevance to the dissertation topic. Both the positive and negative aspects of each data collection method will be studied to ascertain the feasibility and benefits of the approach in relation to the final year dissertation. The Case Study Approach Case studies are used when the researcher intends to support the argument by an in depth analysis of a person, a group of persons, an organisation or a particular project. As the nature of a case study focuses on one aspect of a problem, the conclusion drawn will not be generalised but actually related to on particular event. Although the case study will only focus on one aspect of a theory, it will provide an in depth analysis on it. There are three types of case study designs; The descriptive case study. This is the concept of counting applied to a detailed case. The analytical case study. This is the concept of association and relationship applied to a detailed case. Analytical research means that an element that causes, affects or has an influence on another element has been identified. The element that does the causing is called an independent variable. The element whish is acted upon therefore, is called the dependant variable. The explanatory case study. This entails a theoretical approach to the problem. Linkages among the objects are shown. It also suggests that a single cause can have a specific effect. For example, the researcher collects facts and studies the relationship of one set of facts to another with the hope of finding a relationship between them. Case studies can be complimented by surveys carried out on situations where, how or why questions can be answered by a survey and/or a case study. Using these two approaches in correlation with each other will ensure maximum data is collected and examined more thoroughly. Rational A case study would be particularly relevant to the chosen dissertation. In order to carry out a case study for the dissertation, the author hopes to approach an Irish Company who has been forced to move abroad to analyse their current situation. Using a case study as the primary data collection method would be effective due to its examination of factual information. Questionnaire Method The questionnaire is one of the most widely used data collection techniques used for conducting surveys. It is most suited to a survey whose purpose is clear enough without elaborate explanation. The questionnaire is used for analytical and descriptive surveys in order to find out facts, opinions and views on the current affair in question. There are many advantages and disadvantages, aspects of both are listed below; Advantages: Economy; a questionnaire is an economical way to assembling as much information as possible in terms of finance, human and other resources as you are relaying the questions free of charge to someone in the know. Speed; questionnaires are a fast method of conducting surveys. However, time must be allowed for late returns. Consultation; when questionnaires are posted in advance of the interview, the person being interviewed has the opportunity to avail of information needed which they may not have been aware of previously without checking, in order to give an accurate response. Disadvantages: Must contain simple question; simple questions that are straight forward are necessary to follow easy instructions and definitions. Faults such as ambiguity and vagueness are common. Inflexible technique; mailing questionnaires to companies does not allow the opportunity for probing. All answers must be accepted as final and the opportunity to clarify ambiguity is lost. Accuracy; companies are likely to answer questions according to their public profile rather than the underlying corporate reality. No control over respondents; when posting a questionnaire there is no guarantee that the intended person completes the questionnaire. Rational Although there are many draw backs when using this method of data collection, there are also many positive aspects that it can contribute to the authors dissertation. For example, each questionnaire completed will be unique in both questions and answers. As a result of this, each questionnaire will be tailored made with an individuality in answers, which will help obtain maximum data with minimum effort. The Interview Approach The interview technique is a major method used to collect factual information as well as opinions of those with experience in the area of the chosen topic. It is down to the interviewer to evoke answers that are pertinent to the research hypothesis. The questions and their sequence wording define the structure of the interview. Interviews are suitable when; You know enough about your interviewee so the appropriate questions are asked in a suitable manner. Interpersonal contact is essential to explain and describe the questions. When the research requires an explanation as why the respondents are answering or feeling the way they do, i.e. the answer requires more than a yes/no/agree/disagree answer. There are many types of interviews, for example; formal/informal, inflexible/flexible, standardised and un-standardised, controlled and uncontrolled however the three interviews the author will focus on are; Unstructured, Structured and Semi-structured interview. Unstructured Interview This form of interview uses open ended questions. The questions are often pitched at a very general level so that the researcher can see in what direction the interviewee takes things in their response. This type of interview is generally conducted at the start of a case study as it is an exploratory exercise. It is usually conducted with qualitative research methods. There is no set order or wording of questions, there is no schedule and the researcher is not looking for the same information from each person interviewed. On completion of this type of interview, the researcher may have a list of many factors which should be examined through structure interviews and questionnaires. Semi-structured Interviews This is a more formal interview than the structured interview in that there are a number of specific topics around which the interview can be built. Questions will have open and closed ends, but the questions will not be asked in a specific order or to a schedule. In the semi structured interview, the interviewer has a great deal of freedom to probe various areas and to raise specific queries during the course of the interview. This is achieved by beginning the interview using indirect questions in order to build up a rapport with the respondent, then exploring the specific issues the interviewer has in mind. The task is to discover as much as possible about the specific issues related the subject area. Here are some common characteristics of the semi-structured interview; It takes place with a respondent known to have been involved in a particular experience. It refers to situations that have been analysed prior to the interview. It is focused on the respondents experiences regarding the situations under study. It proceeds on the basis of an interview guide specifying topics related to the research hypothesis. Structured Interview In the structured interview, questions are presented in the same order and with the same wording to all interviewees. The interviewer will have full control on the questionnaire throughout the entire process of the interview. In this technique the questioning may start with open ended questions but will soon move towards a closed question format. There are three assumptions of the structured interview; The respondents have a sufficiently common vocabulary so that it is possible to formulate questions which have the same meaning for each of them. That it is possible to phrase all questions in a form that is equally meaningful to each respondent. Each question and sequence of questions must be identical for each respondent. Therefore the advantages of the structured interview are that i) the answers can be more accurate, ii) The response rate is relatively high and iii) the answers can be explored with finding out why the particular answers are given. Rational The clear advantages that the interview technique has in relation to the dissertation is that the interviewer has a chance to listen to construction professional individual opinions, how the economy has affected them and their business and how it has changed their lifestyle by moving to a foreign country. This in depth analysis of answers from a broad range of respondents allows the researcher to gain a large volume of knowledge from many different perspectives. As the dissertation focuses on construction professional oversees, the author will carry out tele-conference interviews to gain an insight on how these professionals are adapting to working in foreign countries. Desk Study Research Desk study research refers to the methods of primary data collection used by the researcher.  It involves gathering data that already exists either from publications of governmental and non-governmental institutions, free access data on the internet, in professional newspapers and magazines, in annual reports of companies and commercial databases. In many projects, carrying out an initial desk research stage is strongly recommended for the dissertation to gain background knowledge to the topic. Proposed Research Sample The author intends to review previous case studies in relation to Irish construction companies relocating abroad. This is vital for the purpose of the dissertation in order to analyse how the companies are now doing, to determine the problems they have faced and to determine the differences from working in Ireland to working abroad. Below is an article which outlines the issues an Irish construction company may encounter when moving oversees. http://www.engineersireland.ie/media/engineersireland/cpd/successstories/Punch%20and%20Partners%20explore%20overseas%20markets%20through%20CPD.pdf Conclusion The author has explained the differences between qualitative and quantitative research and these methods will be used for carrying out the dissertation. The author also outlined the various types of data research methods and came to the conclusion that fieldwork research (case studies, tele-conference interviews, questionnaires and surveys) and desk study research (textbooks and construction magazines) are the methods that will be adopted for the dissertation. This will be the most effective way in producing a well structured and detailed dissertation.

Effects of Religious Education on Theme and Style of James Joyces The

Effects of Religious Education on Theme and Style of James Joyce's The Portrait of the Artist as a Young Man Although Joyce rejected Catholic beliefs, the influence of his early training and education is pervasive in his work. The parallels between Biblical text and The Portrait of the Artist as a Young Man are abundant. As Cranly says to Stephen, "It is a curious thing, do you know, how your mind is supersaturated with the religion in which you say you disbelieve" (232). The novel progresses in a way that seems Biblical in nature; thematically it compares with the creation and fall of man and/or Lucifer. In addition, the style is at times similar to Biblical text, using familiar rhythm, repetition, phrasing and imagery. As with the Bible, Joyce begins his novel with the importance of the word. He then relates sensual impressions, as if a newly formed creature were experiencing the physical world. Then, as the center of his universe, Stephen also learns the meaning of words and the power of words. He is like Adam bringing order to things by giving them names. But Stephen's knowledge comes not only from the material world, he learns through a sudden-knowing, similar to spiritual understanding, a process Joyce calls intuitive or epiphany. His thirst for knowledge both intellectual and sensual brings him in conflict with his father (Jesuit and heavenly). He falls from grace and experiences hell (through the power of word and his very vivid imagination). Because of his terror of hell he responds at first with repentance, but after reflection, with defiance. At the end of the novel he leaves his homeland, his place of origin, and prepares to begin a new life in a new land. THE WORD In the beginning was the word. Throu... ...because of what has happened to him, but because of his response to those events. He was not the only young Irish boy to have a self-sacrificing saintly mother and an irresponsible drunkard father. He was one of hundreds if not thousands of boys to be indoctrinated and trained by the Jesuits. What made him different was his response and that response was unique to him, and that uniqueness was born in him. So, the ultimate conclusion of the novel is that the artist is born, not made by human ways, but created by the powers of nature and/or God. Works Cited: Joyce, James. The Portrait of the Artist as a Young Man. New York: The Viking Press, Inc., 1958. Joyce, Stanislaus. My Brother's Keeper James Joyce's Early Years. New York: The Viking Press, 1993. Levin, Harry. James Joyce, A Critical Introduction. New York: New Directions Publishing Corporation, 1960. Effects of Religious Education on Theme and Style of James Joyce's The Effects of Religious Education on Theme and Style of James Joyce's The Portrait of the Artist as a Young Man Although Joyce rejected Catholic beliefs, the influence of his early training and education is pervasive in his work. The parallels between Biblical text and The Portrait of the Artist as a Young Man are abundant. As Cranly says to Stephen, "It is a curious thing, do you know, how your mind is supersaturated with the religion in which you say you disbelieve" (232). The novel progresses in a way that seems Biblical in nature; thematically it compares with the creation and fall of man and/or Lucifer. In addition, the style is at times similar to Biblical text, using familiar rhythm, repetition, phrasing and imagery. As with the Bible, Joyce begins his novel with the importance of the word. He then relates sensual impressions, as if a newly formed creature were experiencing the physical world. Then, as the center of his universe, Stephen also learns the meaning of words and the power of words. He is like Adam bringing order to things by giving them names. But Stephen's knowledge comes not only from the material world, he learns through a sudden-knowing, similar to spiritual understanding, a process Joyce calls intuitive or epiphany. His thirst for knowledge both intellectual and sensual brings him in conflict with his father (Jesuit and heavenly). He falls from grace and experiences hell (through the power of word and his very vivid imagination). Because of his terror of hell he responds at first with repentance, but after reflection, with defiance. At the end of the novel he leaves his homeland, his place of origin, and prepares to begin a new life in a new land. THE WORD In the beginning was the word. Throu... ...because of what has happened to him, but because of his response to those events. He was not the only young Irish boy to have a self-sacrificing saintly mother and an irresponsible drunkard father. He was one of hundreds if not thousands of boys to be indoctrinated and trained by the Jesuits. What made him different was his response and that response was unique to him, and that uniqueness was born in him. So, the ultimate conclusion of the novel is that the artist is born, not made by human ways, but created by the powers of nature and/or God. Works Cited: Joyce, James. The Portrait of the Artist as a Young Man. New York: The Viking Press, Inc., 1958. Joyce, Stanislaus. My Brother's Keeper James Joyce's Early Years. New York: The Viking Press, 1993. Levin, Harry. James Joyce, A Critical Introduction. New York: New Directions Publishing Corporation, 1960.

Hope for the Flowers Essay

’’Hope for the flowers’’ is a book that I found at a friend’s place. This book was part of a course on entrepreneurship that he underwent at business school. Hardbound with bright coloured cover and inside pages, the book looks like one created for kindergarten kids. Something that prompted me to give him a quizzical look. His reply was very simple – ’’Just read it’’. I was still sceptical, but considering the fact that the course itself was taken by a pretty successful entrepreneur I gave it the benefit of doubt – after all it was hardly 15 minutes worth of reading and – aren’t we all just kids in adult make up It is the story of two caterpillars – the not so good looking, strong, ambitious, go getting, very male Stripe and the more beautiful, intuitive, perceptive, lovely Yellow. How do I know that she is lovely? – its the illustrations silly. Like all caterpillars do, Stripe bursts out of his tiny egg to come out into a bright and sunny world. He is hungry and wastes no time to begin eating the leaf that he was born on. And then another and another and another until he feels ’’that there must be more to life than just eating and getting bigger’’. Stripe then goes on a ’’fascinating discovery of life’’ that leads him to what he believes is the way to the TOP.It is not an easy path, one must ’’push, shove and trample to go up’’ and it is in this path upwards that he meet Yellow. Yellow is already on the way up. She has convinced herself that it is the only way up, until she meets stripe. And destiny which brings them together also takes them apart. Yellow strikes out on her own, because she is sure there must be some other better way to reach the top. She does not know what that path is and goes on simple faith, building a dark cocoon around herself in the impossible hope that she could be a butterfly. As her guide says ’’It’s what you are meant to become. It flies with beautiful wings and joins the earth to heaven. It drinks only nectar from the flowers and carries the seeds of love from one flower to another. Without butterflies, the world would have fewer flowers.’’ As I read the story the one thing that struck me was the manner in which the author almost perfectly recreated corporate life in the metaphor of a caterpillar’s life. As it turned out I was wrong. This book was NOT written with corporate in mind. It was the outcome of someone ’’sharing comfort with a friend who had just experienced death of someone close’’. Yet it had lent itself so beautifully to the purpose it was assigned (as course material in a business school) and to the imagination of its reader (myself). What is it that makes it so? What is it that makes stripe and yellow ’’fly around the world carrying hope for the flowers and millions of people’’ for more than 25 years now? Is it the universal message that it tries to get across? Is it the simple narrative that is so very accessible? Is it the wonderfully illustrated copy? Is it that rare sometime when everything falls in its right place? I don’t know. What I do know is that you owe it to yourself to take 15 minutes of your time and read it. after all – it is in your destiny that you spread your wings and fly, not crawl, trample, push, kick and climb.

Quiz Computer Forensic & Investigation Essay

Hanley Strappman, 37, was trying to learn about the Computer and Digital Forensics program at Champlain College. He was able to obtain some files, which he put on a floppy disk. To disguise his espionage, he decided to smuggle the floppy back home after altering the files so that they couldn’t be read using the ordinary DOS/Windows file manager. His deception was discovered, however, and the floppy has been recovered. Some of your counterparts have already tried to examine the disk to no avail. Upon discussions with Hanley, he has boasted that there are three files on the disk but that â€Å"You’ll never know what I got!!† You are being provided with a forensically true and accurate copy of Hanley’s floppy disk. You are asked to examine the floppy disk and provide answers to a few questions about the integrity of the data that was recovered (in terms of maintaining the evidentiary chain), the recovery of certain information, and any actions that the suspect may have taken to intentionally delete, hide and/or alter data on the floppy disk. Good Luck! Using the software tools provided to you in class, audit the disk and conduct a full analysis of any artifacts found on the media. The following questions must be completed in the time allotted: The Questions 1. What is the name and address of the person to whom Hanley wrote a letter? Dr. John Watson 8295 Martha Lane Los Alamitos, CA 90720 2. Who is in the picture that Hanley obtained? Lewis Carroll, Edith, Lorina and Alice Lidell 3. What is the information that Hanley supplied in a password-protected form? A file named â€Å"curriculum† in Microsoft Excel format. 4. What are the names of the files on the floppy? Each was hidden or obscured in a different way; indicate how you found the files and how you recovered the information. The file name is cc_stuff.exe Change the format to the .zip format and enter the password to get the information 5. Where did you find the password? By using PRTK software, inside the evidence image at the pwd

Free Essays on Lifes Sanctity. An Analysis Of “Put Me Out Of My Misery, Shoot Me!“ On Euthanasia

Life’s Sanctity â€Å"Do you know what it’s like to be unable to scratch an itch or pull up a blanket? Do you know the horror of ‘living’ with no sensory stimulation other than torturous pain for days upon days, weeks upon weeks, months upon months and years upon years† (Larsen 77)? In â€Å"Put Me Out of My Misery, Shoot Me!† by Ron A. Larsen, there is a very clear message supporting the need for legalized euthanasia. Larsen tries to convince the reader to support assisted suicide by using very explicit details in describing the suffering the old woman is experiencing. He is clearly a supporter of active euthanasia, where an overt effort is made to bring about death, such as administering a lethal injection. â€Å"Push a needle into my veins; press a pillow to my face; put a bullet to my head-as an act of love† (Larsen 78). To make an active effort to put a person out of misery is very controversial, although I agree completely in the patienceâ€⠄¢s or patience guardian’s right to deny any medical treatment. Proponents for euthanasia justify their case on the three moral principles of mercy, autonomy, and justice (Battin 18). Opponents contend that life is too precious for anyone to end it. They also claim that euthanasia would lead to devaluation of human life, because it would force medical professionals and patients’ families to judge the worth of other lives. However, isn’t forcing hopelessly ill patients to continue their suffering and total dependence on others a devaluation of human life? â€Å"And please do not speak to me of the sanctity of life, for this is not life† (Larsen 77). Larsen clearly thinks so. â€Å"For decades I was a beautiful woman-vibrant, charming, athletic, and sexy. Men stared and whistled at me on the street from my teens until I was past sixty. They wanted to mate with me, to possess me† (Larsen 76). Larsen makes us merciful by opening our eyes to the possibility that it m... Free Essays on Lifes Sanctity. An Analysis Of â€Å"Put Me Out Of My Misery, Shoot Me!â€Å" On Euthanasia Free Essays on Lifes Sanctity. An Analysis Of â€Å"Put Me Out Of My Misery, Shoot Me!â€Å" On Euthanasia Life’s Sanctity â€Å"Do you know what it’s like to be unable to scratch an itch or pull up a blanket? Do you know the horror of ‘living’ with no sensory stimulation other than torturous pain for days upon days, weeks upon weeks, months upon months and years upon years† (Larsen 77)? In â€Å"Put Me Out of My Misery, Shoot Me!† by Ron A. Larsen, there is a very clear message supporting the need for legalized euthanasia. Larsen tries to convince the reader to support assisted suicide by using very explicit details in describing the suffering the old woman is experiencing. He is clearly a supporter of active euthanasia, where an overt effort is made to bring about death, such as administering a lethal injection. â€Å"Push a needle into my veins; press a pillow to my face; put a bullet to my head-as an act of love† (Larsen 78). To make an active effort to put a person out of misery is very controversial, although I agree completely in the patienceâ€⠄¢s or patience guardian’s right to deny any medical treatment. Proponents for euthanasia justify their case on the three moral principles of mercy, autonomy, and justice (Battin 18). Opponents contend that life is too precious for anyone to end it. They also claim that euthanasia would lead to devaluation of human life, because it would force medical professionals and patients’ families to judge the worth of other lives. However, isn’t forcing hopelessly ill patients to continue their suffering and total dependence on others a devaluation of human life? â€Å"And please do not speak to me of the sanctity of life, for this is not life† (Larsen 77). Larsen clearly thinks so. â€Å"For decades I was a beautiful woman-vibrant, charming, athletic, and sexy. Men stared and whistled at me on the street from my teens until I was past sixty. They wanted to mate with me, to possess me† (Larsen 76). Larsen makes us merciful by opening our eyes to the possibility that it m...

Effects of Parental Alcoholism on Children essays

Effects of Parental Alcoholism on Children essays The Effects of Parental Alcoholism on Children Until rather recently, the impact of alcoholism was measured by its effect on the alcoholic, by days lost from work and highway fatalities. New research, however, has tended to concentrate on the impact of alcoholism on the family, especially the children of alcoholics. Numerous studies have reported on the familial transmission of alcoholism. It has been shown that alcoholics have more biological relatives with an alcohol problem than do nonalcoholic. Furthermore, these people have a higher probability for developing alcoholism earlier in their lives; and experiencing more severe effects of alcoholism There are in the vicinity of twenty million children under eighteen years of age whom are growing up in households where one or both parents are alcoholic, in the United States alone. These children are the unwilling victims of a disease which generally is the center of their childhood existence, and therefore shapes their personality and behavior as adults. Because of the familial nature of alcoholism children have been identified to be of high risk for developing this illness (Merikangas p.199). Unless something is done to break the patterns initiated during childhood, a significant percentage, (between 50%-60%), of those who dont become alcoholics themselves will marry an alcoholic upon reaching maturity, thereby continuing the cycle of abuse and depression. Studies of the development of drinking behavior recognize the formation of socially appropriate rules about the use of alcohol and the role of the parent behaviors and attitudes in determining drinking patterns (Wilks Clustering of depression, alcoholism and antisocial personality within families has been frequently observed (Merikangas p.199). Alcoholism is a disease of denial, that is, t...